CompARE (https://cinna.upc.edu/compare/) is a web-platform inspired to provide help on issues relating to trials with composite endpoints. CompARE may be used as a tool for calculating the elements needed in the planning phase of clinical trials involving composite endpoints. With its user-friendly interface, CompARE allows to input the main parameters included in the trial -such as the treatment effect on the components of the composite endpoint, and its frequencies of occurrence- and helps provide power and sample size calculations among others.
CompARE comprises two different Shiny apps: one devoted to time-to-event endpoints, the other to binary endpoints.
If you are a newcomer, we recommend starting with the tutorial vignettes. These vignettes provide an introduction to CompARE:
CompAREdesign
R packageThe CompAREdesign
package contains the following functions:
# install.packages("devtools") library(devtools) install_github("CompARE-Composite/CompARE-package")