App features
CompARE is a web-platform inspired to provide help on issues relating to trials with composite endpoints. CompARE may be used as a tool for calculating the elements needed in the planning phase of clinical trials involving composite endpoints. With its user-friendly interface, CompARE allows to input the main parameters included in the trial -such as the treatment effect on the components of the composite endpoint, and its frequencies of occurrence- and helps provide power and sample size calculations among others.
CompARE comprises two different Shiny apps: one devoted to time-to-event endpoints, the other to binary endpoints.
- CompARE for Time-to-event endpoints: Time-to-event app.
- CompARE for Binary endpoints: Binary app.
You can also find the R-package version of CompARE in CRAN CompAREdesign.
Getting Started
If you are a newcomer, we recommend starting with the tutorial vignettes. These vignettes provide an introduction to CompARE:
- Time-to-event Tutorial: Guide document of CompARE for Time-to-event endpoints Time-to-event Tutorial.
- Binary Tutorial: Guide document of CompARE for Binary endpoints Binary Tutorial.
App features
Effect size
Studying the treatment effect for the composite endpoint
Time
to event Binary
Sample Size
Computing the number of patients under different scenarios
Time
to event Binary
Endpoint Selection
Identifying the best endpoint combination for the design
Time
to event Binary
Association
Assessing the degree of association between components
Binary